Mutagenicity Assessment of Airborne Particles in Mexico City

-The Ames’s TA98 strain of Salmonella typhimurium with and without mammalian metabolic activation was used to detect the mutagenic activity of organic chemicals associated with airborne particles. Two kinds of particles: total suspended (TSP) and those particles with an aerodynamic diameter of 10 pm or smaller (PMIO) were collected in glass fiber filters using high-volume samplers during the dry season (Dec,ember 1$189-March 1990) in the Metropolitan Area of Mexico City at five stations of the air quality network belonging to the Ministry of Social Development. Although the highest mass concentrations of particles were obtained from the Northeastern and Southeastern areas, the largest frequency of mutations was found Downtown which indicated that vehicle exhaust was an important source. Contrary to what was expected, the mutagenic responses were higher for PM10 than for TSP samples. On the other h&d, the microsome activation increased significantly the mutagenic activity of the complex mixture, which hinted at the presence of higher amounts of indirect (or promutagens) than direct mutagens both for TSP and PMlO. Key word index: Airborne particles, mutagenicity, Mexico City, PMlO, TSP, Ames test.